一例人感染高致病性禽流感病毒(H5N1)的流行病学调查

Epidemiological investigation of a case of highly pathogenic avian influenza virus infection(H5N1)

目的通过对1例人感染高致病性禽流感病毒(H5N1)的调查分析,为制定人禽流感预防控制措施提供科学依据。方法采用流行病学调查、临床检查、血清学检查和 RT-PCR、 Real-time PCR 法进行分析和诊断。结果发现1例人感染高致病性禽流感病毒(H5N1),经救治无效因呼吸衰竭死亡。患者有明确的病、死禽接触史。采用隔离治疗、个人防护、医学观察、消毒等措施,疫情得到控制,未出现二代病例。结论需加强禽流感疫情监测,采取综合防控措施,预防疫情再次发生。

Objective This study was conducted to investigate and analyze a case of highly pathogenic avian influenza virus infection （HSN1） for the provision of scientific basis for the formulation of measures to prevent and control avian influenza in humans. Methods epidemiological investigation, clinical examination, serological tests, RT-PCR, and real-time PCR were employed for analysis and diagnosis. Results One case of highly pathogenic avian influenza virus infection in humans （HSN1） was found and died of respiratory failure. The patient had a history of contact with diseased and dead birds. The epidemic was put under control through isolated treatment, personal protection, medical observation, sterilization and so on, no second generation case seen. Conclusion Comprehensive measures for the prevention and control of the epidemic need to be taken to reinforce the surveillance of the avian influenza epidemic to prevent it from recurring.