中国大陆第一例人感染高致病性禽流感流行病学调查分析

Epidemiological Investigation of the First Case of Human Infection With the H5N1 Avian Influenza Virus in China's Mainland

目的探讨中国大陆第一例人感染高致病性禽流感感染来源,分析、总结疫情发现与报告、标本采集等方面的经验与不足,为人感染高致病性禽流感防治提供科学依据。方法运用现场流行病学调查与描述流行病学方法。结果患者是由于暴露于病死禽及其所污染的环境而感染;临床医护人员标本采集意识较低、居民对禽流感防治知识及其危害认识不足。结论本例人感染高致病性禽流感为“禽—人”传播,尚无足够的证据证明存在“人传人”现象;建议加大对临床医护人员和居民尤其是农村居民禽流感相关知识的培训,增强临床医护人员对人禽流感的敏感性和标本采集意识,提高普通居民参与禽流感防治的主动性和积极性。

Objective To explore the infection source about the first case of human infection with the avian influenza virus H5N1 in the China's Mainland, analyze and summarize the experience and shortness in discovering, reporting of the epidemic situation and in collecting samples. Methods Field epidemiological investigation, descriptive epidemiological methode were applied. Results The case was infected due to exposure Of the ill/fatal avian with infection of H5N1 avian virus and the contaminated environment. Clinical health - care - workers had poor consciousness of sampling and the inhabitants lacked the knowledge of Avian-Influenza A （H5N1）. Conclusion The case was translated from avian to human, and no sufficiency evidence to support the existence of human- to- human transmission. The knowledge about avian- influenza education must be enhanced to both the health-care- workers and the inhabitants, especially the inhabitants of rural regions.