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后适应从实验室走进导管室的展望

Postconditioning:from Bench to Bedside
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摘要 自从3年前首次发现后适应能显著减少心肌再灌注损伤,已有大量研究证实后适应在多个种属均有效。在不久前的一个小样本临床试验中,后适应对急性心肌梗死后患者的心脏有着显著保护作用。这个研究使得科研人员和临床医生开始关注后适应在人体中的心脏保护作用及其临床应用价值。 Three years ago,postconditioning was observed for the first time to be capable of significantly reducing myocardial reperfusion injury. Since then it has been shown in many studies to be effective in multiple species. A recent small-sample clinical study has shown that postconditioning can protect the heart in humans with ongoing acute myocardial infarction. The study has highlighted the cardioprotective effect of postconditioning in human beings and its clinical value.
出处 《心血管病学进展》 CAS 2006年第3期327-330,共4页 Advances in Cardiovascular Diseases
关键词 心肌缺血 再灌注 心肌梗死 后适应 心肌再灌注损伤 心脏保护 ischemia reperfusion myocardial infarction postconditioning
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参考文献22

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