早产胎膜早破的临床分析

Clinical analysis of pregnancy outcomes on preterm premature rupture of membranes

目的：探讨早产胎膜早破（preterm premature rupture of membranes，PPROM）的妊娠结局。方法：对70例PPROM进行回顾性分析。结果：70例PPROM的潜伏期为1-216．33h，平均48．33h。65．71％的PPROM有易发因素存在。孕28～33周与孕34～37周间PPROM分娩方式的比较，差异有显著性的意义（P〈0．01）。孕28-33周PPROM新生儿发病率和死亡率明显高于孕34-37周者（P〈0．01）。结论：对于孕周小者，尽量延长孕周至34周以上，以降低新生儿发病率和死亡率，尤其对于孕28-33周PPROM宜采取期待疗法，以减少新生儿合并症的发生。

Objective ：To study pregnancy outcome on preterm premature rupture of membranes （PPROM）. Methods：70 cases of PPROM were retrospectively analyzed. Results：The average of latent periods on PPROM was 48 hours and 20 minutes. 65.71% of PPROM had predisposing factors. There was significantly differences in delivery way in patients between at 28 - 33 weeks＇ gestation and at 33 - 37 weeks＇ gestation （ P 〈 0. 01 ）. Neonatal morbidity and mortality were higher in patients at 28 - 33 weeks gestation than those in ones at 33 - 37 weeks gestation （ P 〈 0. 01 ）. Conclusion： In patients with a gestationl age of 28 - 34 weeks, a waiting management scheme was advised to decrease neonatal morbidity. Patients with PPROM should be prolonged more than 34 weeks＇gestation at lease to decrease neonatal mortality.