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肺癌患者血中P物质、生长抑素、可溶性白介素-2受体等含量的变化 被引量：1

Measurement of SP,SS,sIL-2R,TNF in Patients with Lung Neoplasma
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摘要 本文测定68例未经治疗的肺癌患者(包括腺癌38例,小细胞肺癌20例,鳞癌10例)血中P物质(SP)、生长抑素(SS)、可溶性白介素-2受体(sIL-2R)、肿瘤坏死因子(TNF)的浓度.结果表明,肺癌患者SP、SS-sIL-2R、TNF分别比正常组升高1.8倍、2.1倍、2.6倍和1.4倍,肺癌晚期这四项指标明显高于早期,而早期这四项指标仍显著高于正常人,三种类型肺癌间这四项指标无明显差异.结论认为,高浓度的SP、SS、sIL-2R、TNF均可抑制细胞免疫功能,这可能是肿白细胞得以生长的原因之一. Substance P(SP) Somatostatin (SS) soluble Interleukin-2 Receptor (sIL-2R) and Tumor Necrosis Factor (TNF) were Measured in 68 Untreated patients with lung cancer (38 ade-nocarcinoma,20 small cell lung cancer, 10 squamous cell carcinoma). The results showed that SP, SS,sIL-2R and TNF in lung cancer was 1. 8 times, 2. 1 times, 2. 6 times, 1. 4 times higher than those in normal controls,respectively. The four indices in patients with early stage of lung cancer were all lower than those in advanced stage and higher than those in normal controls. Conclusion: The cellular immunological function was reduced in patients with lung cancer due to the high levels of SP,SS,sIL-2R and TNF.
作者 王洪武 段蕴铀 赖莉芬 荣杨
机构地区 海军总医院呼吸内科 海科锐生物技术中心
出处 《海军总医院学报》 1996年第1期26-29,共4页 Journal of Naval General Hospital of PLA
关键词 肺癌 神经调节肽 免疫介质 :Lung neoplasma Neurotransmittors Immunological transmittors
分类号 R734.203 [医药卫生—肿瘤]
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参考文献2

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共引文献20

同被引文献12

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海军总医院学报
1996年 第1期

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