应激和脱发

Stress and Hair Loss

应激是引起脱发的原因之一,应激可能是静止期脱发的主要诱因;可能使以内分泌、感染、遗传或免疫因素为主要病因的脱发(雄激素性脱发、斑秃等)症状加重;脱发引起的情绪低落可能会进一步加重脱发,进而形成恶性循环。除了药物,现在更需要临床医生用全面而谨慎的方法来减轻脱发患者伴随的心理障碍,这将有助于缓解应激,阻断恶性循环并提高患者的生活质量。

Stress has long been implicated as one of the causal factors of hair loss. Stress Is a primary reducer of telogen effluvium,also an aggravating factor of hair loss （e.g., androgenetic alopecia,alopecia areata） mainly induced by endocritic,infectious, genetic or immunological factors. Depression induced by hair loss may aggravate it and induce a self-perpetuating vicious circle. Besides the drugs, comprehensive and cautious strategies are required to relieve the patients＇ psychological pressure, which will help to release the stress, block the vicious circle and raise the patients＇ quality of life. Here we summarize the information about the physiological relationship between stress and hair loss,the way of stress influencing hair growth and the molecular mechanisms of the hair follicles response to stress.