癌基因和抑癌基因研究进展

Advances in Research on Oncogene and Tumor Suppressor Gene

癌基因和抑癌基因的发现和研究是肿瘤研究史上的一个里程碑,标志着肿瘤研究进入了分子时代,从而在更深层次上为阐明基因的结构、表达、调控、功能的改变与肿瘤形成的关系提供了科学依据和可能性,具有重要的理论和实际意义。本文概述了癌基因和抑癌基因的最新研究进展。

Discoveries and researches of oncogene and tumor suppressor gene is a milestone in the history of tumor research. It indicated that tumor research had entered into ＂molecule era＂. It is possible to illuminate the relationship between the alteration of the structure, expression, regulation, function of genes and tumor formation, which is of great significance in theory and practice. In this article, the advance of researches on oncogene and tumor suppressor gene were reviewed.