河北省体循环血管阻力异常的人群分布及相关因素

Distribution of Systemic Vascular Resistance Disorders and Its Related Factors in Hebei Province

目的分析体循环血管阻力异常在健康人群中的分布特点及相关因素的影响。方法采用Bioz·com数字化无创血液动力学监护仪,检测999名健康人体循环血管阻力及收缩压、舒张压、平均动脉压、脉压、心率、心输出量、心脏指数、搏出量、搏出指数、左心射血时间、左心作功量等心功能指标,同时检测了血清总胆固醇及甘油三脂水平,并进行相关因素分析。结果体循环血管阻力异常有随年龄增长而增大的趋势;女性异常发生率显著高于男性(P<0·001)。相关因素分析显示,体循环血管阻力与收缩压、舒张压、平均动脉压、脉压、左心射血时间、体重指数、血清总胆固醇及甘油三脂呈正相关;而与心率、心输出量、心脏指数、搏出量、搏出指数、左心作功量及动脉顺应性呈负相关。其中心输出量和平均动脉压具有独立显著性影响。结论体循环血管阻力异常与年龄、性别及血压水平密切相关,其可能是早期心血管损伤的一个标志。

Objective To analyze the distribution features of systemic vascular resistance （SVR） disorder in healthy subjects in Hebei province. Methods SVR and systolic blood pressure （SBP） , diastolic blood pressure （DBP） , mean arterial pressure （MAP） , pulse pressure （PP） , heart rate （HR） , cardiac output （CO） , cardiac index （CI） , stroke volume （SV） , stroke index （SI） , left ventricular ejection time （LVET）, left cardiac work （LCW） and cardiovascular function were determined with Bioz. com Cardio Dynamics. Total cholesterol （TC） , triglyceride （TG） and influencing factor were tested by automated hematology analyzer in 999 healthy subjects living in Hebei province. Results SVR disorder gradually increased with the ageing in healthy subjects and the prevalences of SVR disorders was higher among females than among males （ P 〈 0. 001 ） . SVR was positively correlated with SBP, DBP, MAP, PP, LVET, body mass index （BMI） , TC, and TG, and was inversely associated with HR, CO, CI, SV, SI, LCW, and arterial compliance （ AC ）. CO and MAP were independent influencing factors with SVR. Conclusion SVR disorder is associated with age, sex, and blood pressure in populations in Hebei province and may be a marker of vascular injury.