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前手性酮的不对称还原(Ⅰ) 被引量：1

Asymmetric Reduction of Prochiral Ketones
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摘要 综述了前手性酮的不对称还原方法及其近年来的新进展.包括手性恶唑硼烷类催化剂的应用,使用手性改型氢化铝锂的还原,手性修饰的硼氢化钠或硼氢化钾的应用,具有膦酰胺结构的手性催化剂的应用,手性金属络合物催化氢化不对称还原,不对称相转移催化还原,酶催化不对称还原. In this review, asymmetric reduction of prochiral ketones and its recent advances have been described,including application of chiral oxazaborolidine catalysts, reduction by chirally modified lithium aluminum hydride reagents, application of chirally modified sodium borohydride or potassium borohydride, application of cbiral phosphoramide catalysts, transfer hydrogenation of prochiral ketones catalyzed by chiral metal complexes,asymmetric reduction of prochiral ketones by phase-transfer catalysis, enantioselective reduction of ketones with enzyme.
作者 周忠强
机构地区 中南民族大学化学与材料科学学院催化材料科学湖北省重点实验室
出处 《中南民族大学学报（自然科学版）》 CAS 2006年第1期22-27,31,共7页 Journal of South-Central University for Nationalities：Natural Science Edition
基金 湖北省自然科学基金资助项目(2003ABA070) 中南民族大学自然科学基金资助项目
关键词 前手性酮 不对称还原 不对称催化 对映选择性 prochiral ketones asymmetric reduction asymmetric catalysis enantionselective
分类号 O621.34 [理学—有机化学]
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参考文献40

  • 1崔建国,晏日安,曾陇梅.酮的不对称还原[J].有机化学,1998,18(6):521-531. 被引量：7
  • 2Corey E J, Bakshi R K, Shibata S, et al. A stable and easily prepared catalyst for the enantioselective reduction of ketones: application to multistep synthesis[J]. J Am Chem Soc,1987,109(25):7925-7926.
  • 3Jiang B, Feng Y, Zheng J. Highly enantioselective reduction of achiral ketones with NaBH4/Me3SiC1 catalyzed by (S)-α, α-diphenylpyrrolidinemethanol[J]. Tetrahedron Letters, 2000,41 (52): 10281-10283.
  • 4Kanth J V B, Brown H C. A new catalytic enantioselective reducing reagent system from -α,α-diphenylpyrrolidinemet hanoi and 9-borabicyclo nonane especially effective for hindered and substituted aralkylketones[J].Tetrahedron, 2002,58(6): 1069-1074.
  • 5Salunkhe A M, Burkhard E R. Highly enantioselective reduction of prochiral ketones with N, N-diethylaniline borane (DEANB) in oxazaborolidine catalyzed reductions [J].Tetrahedron Letters, 1997, 38(9):1 523-1 526.
  • 6Huertas R E, Corella J A, Soderquist J A.Asymmetric oxazaborolidine-catalyzed reduction of prochiral ketones with N-tert butyl-N-trimethylsilylamine-borarte [J]. Tetrahedron Letters, 2003, 44(24):4 435-4 437.
  • 7Xu J, Su X, Zhang Q. Preparation of highly enantiomerically pure linear secondary alcohols via asymmetric reduction of prochiral ketones with borane[J]. Tetrahedron Asymmetry, 2003,14(13) :1781-1786.
  • 8Kawanami Y, Murao S, Ohga T, et al. Practical enantioselective reduction of ketones using oxazaborolidine catalyst generated in situ from lactam alcohol and borane[J]. Tetrahedron,2003,59(42):8411-8414.
  • 9Zhang Y, Du D, Chen X, et al. Enantiospecific synthesis of pyridinylmethyl pyrrolidine-methanols and catalytic asymmetric borane reduction of prochiral ketones [J]. Tetrahedron Asymmetry,2004,15 (1) : 177-182.
  • 10Li X, Yeung C, Chan A S C, et al. New 1,3-amino alcohols derived from ketopinie acid and their application in catalytic enantioseleetive reduction of prochiral ketones [J]. Tetrahedron Asymmetry,1999,10(4):759-763.

二级参考文献56

共引文献31

同被引文献9

  • 1思洋,刘乐乐,张廓,姜萍萍.氨基酸甲乙酯的合成及纯化[J].内蒙古医学院学报,2005,27(1):33-34. 被引量：18
  • 2[4]Corey E J,Bakshi R K,Shibata S,et al.Highly enantioselective borane reduction of ketones catalyzed by chiral oxazaborolidines.Mechanism and synthetic implications[J].J Am Chem Soc.1987,109(18):5 551-5 553.
  • 3[5]Periasamy M,Kanth J V B,Prasad A S B.Convenient procedures for the asymmetric reductions utilizing α,α-diphenyl-pyrrolidinemethanol and borane complexes generated using the I2/NaBH4 system[J].Tetrahedron,1994,50 (21):6411-6 416.
  • 4[6]Brown H C,Tierney P A.The reaction of lewis acids of boron with sodium hydride and borohydride[J].J Am Chem Soc,1958,80(7):1 552-1 558.
  • 5[7]Brown H C,Murray K J,Murray L J,et al.Hydroboration.V.A Study of convenient new preparative procedures for the hydroboration of olefins[J].J Am Chem Soc,1960,82(16):4 233-4241.
  • 6[9]Itsuno S,Nakano M,Miyazaki K,et al.Asymmetric synthesis using chirally modified borohydrides.Part 3.Enantioselective reduction of ketones and oxime ethers with reagents prepared from borane and chiral amino alcohols[J].J Chem Soc Perkin Trans I,1985,(10):2 039-2 044.
  • 7[11]Basavaiah D,Reddy G J,Rao K V.Toward effective chiral catalysts containing the N -P=O structural framework for the borane-mediated asymmetric reduction of prochiral ketones[J].Tetrahedron Asymmetry,2004,15(12):1 881-1 888.
  • 8杨晓武,倪京满,王锐,潘鑫复.(S)-α,α’-二苯基-2-吡咯烷甲醇的简便合成[J].高等学校化学学报,1997,18(6):911-913. 被引量：8
  • 9崔建国,晏日安,曾陇梅.酮的不对称还原[J].有机化学,1998,18(6):521-531. 被引量：7

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中南民族大学学报（自然科学版）
2006年 第1期

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