期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

NiFe_2O_4-SiO_2纳米复合微粒的制备和表征

The preparation and characterization of NiFe_2O_4-SiO_2 nanocomposite particles
下载PDF
导出
摘要 合成了NiFe2O4-SiO2纳米复合微粒,借助傅立叶变换红外光谱仪(FT-IR)、X射线衍射仪(XRD)、透射电子显微镜(TEM)等分析手段对样品的成分、结构及形貌进行了表征,利用振动样品磁场计(VSM)测定了磁核及其复合微粒的磁学性能,并在pH=6的条件下测定了样品对溴代十六烷基吡啶的饱和吸附量.结果表明:合成的纳米复合微粒分布均匀,具有磁性和吸附性能,在磁靶向治疗中具有潜在的应用价值. The nanocomposite particles of NiFe2O4- SiO2 are synthesized. Their component, crystal structure, morphology and magnetic property are characterized by FT-IR, XRD, TEM and VSM, respectively. The adsorption of products for cetylpyridinium bromide （CPB） is also measured in the solution phase. The results indicate that the resultant products with uniform size exhibit magnetism and adsorption properties, so they have potential value of applications in magnetic drug targeting.
作者 赵红晓 孔超 杨玉英 尚秀丽 胡中爱
机构地区 西北师范大学化学化工学院甘肃省高分子材料重点实验室
出处 《西北师范大学学报（自然科学版）》 CAS 2006年第3期66-69,共4页 Journal of Northwest Normal University(Natural Science)
基金 甘肃省科技攻关项目(2GS035-A52-026) 西北师范大学科技创新工程资助项目(NWNU-KJCXGC-01)
关键词 NIFE2O4 SIO2 纳米复合微粒 磁性 NiFe2O4 SiO2 nanocomposite particle magnetism
分类号 O614.81 [理学—无机化学] O647.3 [理学—物理化学]
  • 相关文献

参考文献13

  • 1XU Hua, SONG Tao, BAO Xiu-qi, et al. Sitedirected research of magnetic nanoparticles in magnetic drug targeting[J]. Journal of Magnetis and Magnetic Materials, 2005, 293(1): 514-519.
  • 2RAMAZAN A, MICHAEL A Z, RICHARD O C,et al. Synthesis, characterization and targeting of biodegradable magnetic nanocomposite particles by external magnetic fields[J]. Journal of Magnetism and Magnetic Materials, 2005, 292: 108-119.
  • 3WILSON M W, KERI.AN R K, FIDEI.MAN N A,et al. Hepatocellular carcinoma: regional therapy with a magnetic targeted carrier bound to doxorubicin in a dual MR imaging/conventional angiography suiteinitial experience with four patients[J]. Radiology,2004, 230: 287-293.
  • 4RUDGE S R. Preparation, characterization, and performance of magnetic iron-carbon composite microparticles for chemotherapy[J].Biomaterials.2000, 21(14): 1411-1420.
  • 5LUBBE A S. Clinical applications of magnetic drug targeting[J]. J Surgical Research, 2001, 95 (2):200-206.
  • 6GOODWIN S. Targeting and retention of magnetic targeted carriers (MTCs) enhancing inrra - arterial chemotherapy [J], Journal of Magnetism and Magnetic Materials, 1999, 194(1-3):132-139.
  • 7LUBBE A S, Physiological aspects in magnetic drugtargering[J], Journal of Magnetism and Magnetic Materials, 1999, 194(1-3): 149-155.
  • 8张阳德,龚连生.磁性阿霉素白蛋白纳米粒的研制[J].中国现代医学杂志,2001,11(3):1-3. 被引量：53
  • 9蒋新宇,周春山,张俊山,杨娟玉.导向药物用纳米Fe_3O_4磁性粒子的制备及表征[J].中南工业大学学报,2003,34(5):516-520. 被引量：22
  • 10SATYANARAYANA L, REDDY K M,MANORAMA S V. Nanosized spinel NiFe2O4: a novel material for the detection of liquefied petroleum gas in air [J]. Materials Chemistry and Physics,2003, 82(1): 21-26.

二级参考文献18

  • 1[1]Widder KJ, Senyei AE, Scarpelli DG.Magnetic microspheres: A model system for site Specific drug delivery in vivo.Proc.Soc Exp.Biol Med, 1978; 158 (1): 141～146
  • 2[2]Gupta PK,Hung CT, Perrier DG.Albumin microspheres.Ⅱ .Effect of stabilization temperature on the release of adriamycin.Int J Pharm, 1986; 33( 1～3 ): 147～153
  • 3[3]Gupta PK, Hung CT, Perrier DG.Albumin mierospheres.Ⅲ.Syn-thesis and characteriztion of microspheres containing adriamycin and magnetite.Int.J Pharm, 1988; 43 (1～2): 167～177
  • 4[4]Gupta PK, Hung CT.Comparative disposition of adriamycin deliv-ered via magnetic albumin micropheres in presence and absence of magnetic field in rats.Life Sci, 1990;46(7):471～479
  • 5[5]Gallo JM,Gupta PK,Hung CT,et a1.Evaluation of drug delivery following the administration of magnetic elbuin microspheres containing adriamycin to the rat,1989;78(3):190～194
  • 6[6]Senyei AE,Reich SD,Gonczy C,et a1.In vivo kinetics of magnetical-ly targeted low - dose doxorubicin.J Pharm Sci, 1981 ;70(4 ) :389～391
  • 7[7]Bachur NR, Moore AL, Bemstein JG, et a1.Tissue distribution and disposition of daunomycin (NSC- 82151) in mice: fluorometric and isotopic methods.Cancer Chemother Rep.Part 1,1970;54(1):89～94
  • 8[8]Benjamin RS, Riggs CE,Bachur NR, et a1.Plasma pharmacokinetics of adriamycin and its metabolites in human with ormal hepatic and renal function.Cancer Res, 1977;37(5): 1416～1420
  • 9[9]Drisooll CF,Morris RM,Sanyei AE,et a1.Magnetic tsrgeting of mi-corspheres in blood flow.Microvas Res, 1984;27(2):353～369
  • 10[10].Gupta PK,Gallo JM,Hung CT,et a1.Influence of stabilization tem-perature on the entrapment of adriamycin in albumin microspheres.Drug Der 1nd Pharm, 1987;13(8):1471～1482

共引文献72

西北师范大学学报（自然科学版）
2006年 第3期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部