2-乙基蒽酮的合成研究

Synthesis of 2-Ethylanthrone

以锡粉和36%～38%盐酸还原2-乙基蒽醌来合成2-乙基蒽酮,对合成过程中加料方式、回流时间、原料配比、溶剂种类等影响因素进行考察,并采用高效液相色谱对样品进行分析,得出较优的反应条件为:以冰乙酸为溶剂,n(2-乙基蒽醌)∶n(锡粉)=1∶2,每隔10min加一次盐酸,约在2h加完,回流1.5h,在此条件下合成的2-乙基蒽酮的总含量为86%。

2-Ethylanthrone was synthesized using stannum powder and hydrochloric acid to deoxidize 2- ethylanthraquinone. Effects of adding material mode, refluxing time, reactant proportion and solvents on synthesis of 2-ethylanthrone were investigated, and the sample content was determined by HPLC. The optimal conditions were obtained as follow： acetic acid as solvent, n （2-ethylanthraquinone）：n （stannum powder）=1：2, adding hydrochloric acid once per 10 min, finished in 2 h, and refluxing 1.5 h. The total content of 2-ethylanthrone was 86%.