摘要
胎儿前脑无叶无裂(holoprecephaly,HPE)畸形是在早期胚胎发育过程中由于前脑无分裂或分裂不全引起的脑先天发育异常。虽然该病发生率低,但预后极差,因此,早期发现、诊断HPE畸形十分重要。既往诊断该病大多是在新生儿或儿童期由CT或病理发现。自1980年Kurtz等第一次描述了HPE畸形的产前超声以来,产前超声对胎儿的诊断在国外已陆续见有报道,但国内的报道很少,现将我院近年来14例胎儿HPE的超声表现报道如下。
出处
《中华围产医学杂志》
CAS
2006年第2期98-99,T0003,共3页
Chinese Journal of Perinatal Medicine
基金
首都医学发展基金资助(2002-3051)
参考文献7
-
1Kurtz AB,Wapner RJ,Rubin CS,et al.Ultrasound criteria for in utero diagnosis of microcephaly.J Clin Ultrasound,1980,8:11-16.
-
2Callen Peter W.Ultrasonography in Obstetrics and Gynecology.4th.Philadelphia:W.B.Saunders Com,2000.289-290.
-
3顾海琴,李松,洪世欣,赵平,C.莫尔,RJ.贝利,李竹.全前脑综合征临床表现[J].中国优生优育(1990-2002上半年),1998,9(1):35-35. 被引量:3
-
4Lai TH,Chang CH,Yu CH,et al.Prenatal diagnosis of alobar holoprosencephaly by two-dimensional and three-dimensional ultrasound.Prenat Diagn,2000,20:400-403.
-
5Peebles DM.Holoprosencephaly.Prenat Diagn,1998,18:477-480.
-
6周柳英,陈德新,杨家翔,项莉亚.胎儿全前脑并颜面部畸形超声表现1例[J].中华超声影像学杂志,2004,13(6):466-466. 被引量:1
-
7Blaas HG,Eriksson AG,Salvesen KA,et al.Brains and faces in holoprosencephaly:pre-and postnatal description of 30 cases.Ultrasound Obstet Gynecol,2002,19:24-38.
二级参考文献1
-
1李松,洪世欣,顾海琴,赵平,王玫,陈新,C.莫尔,R.J.贝利,李竹.医学体表影像在出生缺陷监测中作用的评价[J].中国优生优育(1990-2002上半年),1996,7(2):49-52. 被引量:2
同被引文献11
-
1何丽娟,高秋,曹毅,叶明光,施全.全前脑综合征—11例报告[J].中国优生与遗传杂志,2006,14(3):104-105. 被引量:5
-
2Joo GJ, Beke A, Papp C, et al. Prenatal diagnosis, phenotypic and obstetric characteristics of holoprosencephaly[ J]. Fetal Diagn Ther, 2005,20( 3 ) : 161 - 166.
-
3Bendavid C, Dubourg C, Gicquel I, et al. Molecular evaluation of foetuses with holoprosencephaly shows high incidence of microde- letions in the HPE genes [ J ]. Hum Genet,2006,119 (1 -2) :1 -8.
-
4李胜利.胎儿产前畸形超声诊断[M].北京:人民军医出版社,2004.157-159.
-
5Callen PW. Uhrasonography in obstertrics and gynecology [ M ]. 4th Philadelphia: W. B. Saunders Com,2000.289-290.
-
6MacGregor AR.Pathology of infancy and childhood[]..1960
-
7Hsu TY,Chang SY,Ou CY,et al.First trimester diagnosis of holo-prosencephaly and cyclopia with tripioidy by transvaginal three-dimensional ultrasonography[].European Journal of Obstetrics Gynecology and Reproductive Biology.2001
-
8MacGregor AR.Pathology of infancy and childhood[]..1960
-
9Hsu TY,Chang SY,Ou CY,et al.First trimester diagnosis of holo-prosencephaly and cyclopia with tripioidy by transvaginal three-dimensional ultrasonography[].European Journal of Obstetrics Gynecology and Reproductive Biology.2001
-
10王欣煜.全前脑畸形一例[J].中华围产医学杂志,2008,11(6):436-437. 被引量:1
引证文献4
-
1孙小平,黄瑛,郑莉华,孟红哲.产前超声诊断胎儿前脑无裂畸形并喙鼻1例[J].临床超声医学杂志,2007,9(11):647-647.
-
2孙小平,黄瑛,郑莉华,孟红哲.超声诊断胎儿前脑无叶无裂畸形并单鼻孔1例[J].医学影像学杂志,2008,18(3):252-252.
-
3宋凤菊,张燕,孙小平.13例全前脑的回顾性分析[J].中国优生与遗传杂志,2011,19(7):100-100.
-
4葛素梅,邢宝玲,强贤,何晶,唐正华.胎儿多发性畸形尸检1例并文献复习[J].中国优生与遗传杂志,2013,21(2):102-103.
-
1吴影,陈汉松,翁寿向,杨佩浓,徐铖.胎儿前脑无叶无裂畸形一例[J].中华病理学杂志,2007,36(2):140-141. 被引量:2
-
2马月霞.宫颈炎康栓联合波姆光治疗宫颈炎疗效观察[J].大家健康(学术版),2015(18).
-
3陈建贞.胎儿全前脑畸形的产前超声诊断[J].中国医师杂志,2012,14(6):818-819. 被引量:3
-
4李学广.胎儿全前脑畸形的超声诊断分析[J].医学影像学杂志,2010,20(7):970-970. 被引量:2
-
5魏庆云,郑平勇.宫腔镜治疗子宫内膜息肉后放置曼月乐的临床疗效[J].中国妇幼健康研究,2013,24(1):89-91. 被引量:12
-
6吕东坡,王东明,滕秀秀,王健,李爱武,郭明兴.Neuroligin1基因在Wistar大鼠胚胎肠神经系统中的表达及意义[J].中华小儿外科杂志,2015,36(11):851-855.
-
7孙小平,黄瑛,郑莉华,孟红哲.超声诊断胎儿前脑无叶无裂畸形并单鼻孔1例[J].医学影像学杂志,2008,18(3):252-252.
-
8围产期监护和新生儿[J].中国计划生育和妇产科,1997(1):30-35.
-
9吕慧玲,陈涛涛,焦北鱼,王蕾.全前脑的产前超声诊断与染色体核型分析[J].中华超声影像学杂志,2009,18(1):91-91. 被引量:1
-
10陈萍,孔慧敏.孕12周诊断胎儿全前脑一例[J].中国产前诊断杂志(电子版),2011,3(3):51-52.