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MSCs对肾脏缺血性损伤的作用

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摘要 间充质干细胞(MSC)是一类具有高度自我更新和多向分化潜能的成体干细胞。有大量的实验肯定了骨髓来源的MSCs能够有效的改善急性肾脏的缺血性损伤,恢复肾功能,但具体的机制,究竟是通过MSCs分化为肾脏实质细胞,还是减轻炎症等其他机制尚有争论。本文主要对干细胞的来源,MSCs主要的生物学特征,以及MSCs对肾脏缺血性损伤的治疗机制进行了综述。
出处 《国际泌尿系统杂志》 2006年第3期383-386,共4页 International Journal of Urology and Nephrology
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