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线粒体DNA突变及其在生物剂量估算中的应用探讨

Mitochondrial DNA Mutations and Its Application to Biodosimetry
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摘要 介绍了线粒体DNA(mtDNA)的结构特点和功能,对突变类型和可能的机制进行了分析。着重阐述了电离辐射所致的mtDNA突变,对利用mtDNA突变建立辐射生物剂量计的可行性作了初步探讨。 In this article, the structural characteristics and function of mitochondrial DNA （mDNA） are described, with types and possible mechanisms of mtDNA mutations analysed. Emphasis is on the relationship between radiation exposure and mtDNA mutations.
作者 刘玉龙 吕玉民
机构地区 苏州大学附属第二医院 河南省职业病防治研究所
出处 《辐射防护通讯》 2006年第2期27-30,34,共5页 Radiation Protection Bulletin
关键词 MTDNA 突变 电离辐射 生物剂量 Mitochondrial DNA Mutation Radiation exposure Biodosimetry
分类号 Q75 [生物学—分子生物学] Q691 [生物学—生物物理学]
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参考文献18

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二级参考文献9

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辐射防护通讯
2006年 第2期

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