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格拉司琼防治肿瘤化疗所致恶心、呕吐的临床观察 被引量:1

CLINICAL STUDY OF GRANISETRON PREVENTING AND CURING NAUSEA AND VOMITING CAUSED BY TUMOR CHEMOTHERAPY
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摘要 目的:观察格拉司琼对恶性肿瘤化疗所致恶心、呕吐的临床疗效。方法:38例接受联合化疗的恶性肿瘤病人,随机分格拉司琼组与胃复安组比较治疗效果。结果:格拉司琼组对恶心、呕吐的完全控制率和有效控制率明显优于胃复安组(P<0.05)。结论:格拉司琼可作为预防化疗引起的恶心、呕吐的优选药物。 Objective: To investigate the clinical curative effectiveness of granisetron for nausea and vomiting caused by tumor chemotherapy. Methods: Thirty-eight cases with malignancy receiving combination chemotherapy were divided at random into 2 groups (with granisetron or metoclopramide). The anticmetic efficacy was compared between the 2 groups. Results: Granisetron was superior to metoclopramide in the prevention of nausea and vomiting with significant difference (P 〈 0.05). Conclusion: Granisetron is a good choice of drug in the prevention of nausea and vomiting caused by tumor chemotherapy.
作者 苏乌云
出处 《内蒙古医学院学报》 2006年第1期12-13,共2页 Acta Academiae Medicinae Neimongol
关键词 格拉司琼 药物疗法 副作用 呕吐 granisetron pharmacotherapy side effect vomiting
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参考文献2

  • 1Blower PA.Pharmacologic profile of oral granisetron (Kytris tablets)[J].Semin Oncol,1995;22(4):3-5
  • 2雷妍玮.盐酸格拉司琼对含顺铂联合化疗中的止吐作用[J].实用癌症杂志,2001,15(5):465-471.

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