摘要
脑钠肽(BNP)主要由心室分泌,血浆浓度与心室体积或压力负荷程度呈正比。具有很强的排钠、利尿、扩张血管、抑制肾素-血管紧张素-醛固酮系统(RAAS)和交感神经系统活性作用,有助于充血性心力衰竭的诊断、疗效监测、预后评估和治疗。该文就BNP的生物学特性、检测方法及其在儿童心血管疾病中的临床应用简要综述。
Brain natriuretic peptide （BNP） is mainly secreted from the cardiac ventricles and its plasma concentration is positive correlated with the pressure or volume overload of ventricular It has strong action of natriuresis, diuresis, vasodilation, inhibition of rennin-angiotensin-aldosterone system and sympathic nervous system. The detection of BNP may be helpful to the diagnosis, efficacy monitoring, prognosis evaluation and therapy of congestive heart failure. This article simply reviews the BNP about its biology character, detection method and its application in children with cardiovascular diseades.
出处
《医学综述》
2006年第9期526-529,共4页
Medical Recapitulate
关键词
心力衰竭
脑钠肽
诊断
治疗
Congestive heart failure
Brain natriuretic peptide
Diagnosis
Treatment
