女性腰椎骨密度随年龄的变化趋势研究

THE ESTIMATION OF BONE MINERAL DENSITY OF THE LUMBAR SPINE AMONG FEMALE BY GENERAL LINEAR MODEL.

目的:探讨控制体重以及中心效应的影响后,我国女性腰椎骨密度随年龄的变化趋势。方法:根据研究资料的特点,采用一般线性模型,拟合我国女性腰椎骨密度的变化曲线。结果:年龄与女性腰椎骨密度呈3次回归曲线关系,在纳入协变量体重后,年龄多项式的系数发生了不同程度的改变,并且在控制中心效应后,模型拟合的效果有了进一步的提高。结论:在拟合腰椎骨密度随年龄变化的曲线时,利用一般线性模型控制体重以及中心效应的影响后,可获得更加准确的回归系数及标准误的估计。

Objective： To explore the age-related change of bone mineral density （BMD） of the lumbar spine among the female after controlling the following influential factors： weight and the center effect. Methods： According to the characters of the data, the general linear model was used to fit the BMD curve. Results= The cubic regession was performed on the fitting curve of age - related change of BMD of the lumbar spine anaong the female. The regression coefficients were changed in different extent after the influential factors were involved. Conclusion： The more accurate regression coefficients and the standard errors were obtained by adjusting the weight and the center effect in general linear model.