10502例体检者血糖、血脂和尿酸的检测

THE DETECTION OF GLUCOSE,BLOOD LIPID,URIC ACID IN 10502 HEALTHY PERSONS.

目的：了解成人各年龄段空腹血糖、胆固醇、甘油三酯和尿酸水平。方法：用酶法检测体检者空腹血清总胆固醇（TC）、甘油三酯（TG）、血尿酸（UA）水平，用电极法检测GLU水平。结果：各年龄组血糖结果、空腹血糖受损率和糖尿病阳性率差异有统计学意义（P〈0．05）。50岁以前，TC和TG结果随年龄增加有所增高（P〈0．05），50岁以后，维持相对稳定水平（P〉0．05），高胆固醇阳性率在50岁前随年龄增加（P〈0．01），50岁后变化不大（P〉0．05），高甘油三酯阳性率在40岁前随年龄增加（P〈0．01），40岁后除60～岁组发病最高，与各年龄组差异有统计学意义（P〈0．01）外，其它3个年龄组阳性率差异无统计学意义（P〉0．05）。尿酸浓度及高尿酸血症阳性率均是70岁以上组最高（为374．743±88．831μmol／L、28．3％），与其它各组差异有统计学意义（P〈0．01），男性30～49岁年龄段的尿酸结果（376．208±68．818／anol／L）虽较≥70岁组（387．638土87．838μmol／L）低，但却明显高于其于各年龄组（P〈0．05）。总体男、女之间各项结果、糖尿病阳性率、高胆固醇血症、高甘油三酯、高尿酸血症阳性率差异有统计学意义（P〈0．05），而空腹血糖受损率的差异却无统计学意义（P〉0．05）。结论：随年龄增长，空腹血糖受损、糖尿病、高脂血症发病率增加；30～49岁年龄段的男性尿酸结果呈现高水平状态；中、壮年的男性和绝经前后的女性是高脂血症和高尿酸血症的易发人群。

Objective： To study the levels of fasting serum glucose （GLU）, total cholesterol （TC）, triglyceride （TG） and uric acid （UA） in adult. Methods： The levels of fasting TC, TG and UA of 10502 adults were measured enzymatically and fasting glucose level was measured by electrode. Results： The level of GLU, the ratios of impaired fasting glucose （IFG） and the positive rate of diabetes were significant difference among all age groups. The levels of TC and TG were increased significantly with age in those younger than 50-year-old （P 〈 0.05）, but no same change was found in those older than 50-year-old. The ratio of hypercholesterolemia was also increased significantly with age in those younger than 50-year-old （P〈0.05）, hut no significant change was found in those older than 50-year-old. The ratio of hypertriglyceridemia was increased significantly with age in younger than 40-year-old groups （P〈0.05）, but no same change was found in groups older than 40-year-old except the group of 60-70 years old. The level and ratio of hyperuricemia was found significant higher in group ≥70-year-old （374.743 ± 88.831 μmol/L, 28. 3% ）, （P〈 0. 05）. Meanwhile the levels of UA in male were much higher in the groups of 30-49 years old （376.208 ± 68.818 μmol/L） than other groups except ≥70-year-old group （387.638±87.838 μmol/L）. All examined results of all groups including the ratios of hypercholesterolemia, hypertriglyceridemia, and hyperuricemia were all found higher in male than that in female. Conclusion： The ratios of IFG, diabetes incidence and hyperlipidaemia incidence were increased with age. And the level of UA in male was also high at the age of 30 to 49. The ratios of hyperlipidaemia and hyperuricemia were much higher in mature male and menopause female.