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结核分枝杆菌重组耻垢分枝杆菌疫苗的研究进展 被引量:6

Update on vaccine of recombinant mycobacteria smegmatis of Mycobacteria tuberculosis
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摘要 结核分枝杆菌引起的结核病是一种人兽共患的慢性传染病,短程督导化疗是治疗该病的主要措施,卡介苗是预防该病的唯一疫苗,但其免疫效果极不稳定。文章介绍了4种结核分枝杆菌重组耻垢分枝杆菌疫苗的构建及其免疫机制等方面的研究进展。 Tuberculosis(TB) caused by Mycobacteria tuberculosis (MTB) is one type of zoonotic, chronic and infectious disease, directly observed treatment short-course(DOTS) is a major measure to treat TB, bacillus Calmette-Guerin(BCG) is an only vaccine to prevent TB, but its immune efficacy is not constant. This article clarifies the advance in the research of construction and its immune responses of 4 types of recombinant Mycobacterium smegmatis vaccines of MTB.
出处 《中国病原生物学杂志》 CSCD 2006年第2期148-149,152,共3页 Journal of Pathogen Biology
基金 国家自然科学基金(No.30500423) 教育部重点项目(No.205131) 重庆市科委攻关计划(No.03-43-8) 重庆市教委科研基金(No.KJ050313) 重庆市卫生局科研基金(No.03-2-099和05-2-203)资助项目。
关键词 医学免疫学 重组耻垢分支杆菌疫苗 综述 结核分枝杆菌 Medical immunology recombinant Mycobacterium smegmatis vaccine review Mycobacteria tuberculosis
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