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早产儿视网膜病变患儿血中SOD活力及MDA含量测定 被引量:2

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摘要 目的通过检测早产儿视网膜病变(retinopathy of prematurity,ROP)患儿血中超氧化物歧化酶(super-oxide dismutase,SOD)活性及丙二醛(malondialdehyde,MDA)含量,探讨氧自由基损伤在ROP发病中的作用。方法对41例ROP患儿及40例无ROP的早产儿分别检测血清SOD活性及血浆MDA含量。结果ROP组与无ROP组血清SOD活性分别为(62.89±11.23)KU/L和(79±10.29)KU/L(P<0.01),血浆MDA含量分别为(4.73±0.33)nmol/L和(3.47±0.42)nmol/L(P<0.01),二者差异均有显著性。结论氧自由基损伤与ROP的发生有关联,对其抗氧化治疗是必要的。
出处 《广东医学》 CAS CSCD 北大核心 2006年第5期712-713,共2页 Guangdong Medical Journal
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