摘要
The reinforcing effects on hydroxyapatite （ abbreviated HA ） of phosphate glass additives were researched. The samples of reinforced HA （ abbreviated RHA ） and control material were prepared and then percutaneously implanted in the skin of experiment animal. The histomorphology of the part skin tissue were observed. By a biomimetic process, the method and conditions of forming HA coating on the surface of medical silicon rubber （ abbreviated MSR ） were stndied. The results illustrate that the phosphate glass additives have obvious reinforcing effects on HA. In the percutaueous implantation test, neither clear infiltration of inflammatory cells nor marked downgrowth of epidermis was observed for the part tissue suerounded RHA. The surface modification of MSR for percutaneous access could be attained by biomimetice synthesis of HA coating.
The reinforcing effects on hydroxyapatite （ abbreviated HA ） of phosphate glass additives were researched. The samples of reinforced HA （ abbreviated RHA ） and control material were prepared and then percutaneously implanted in the skin of experiment animal. The histomorphology of the part skin tissue were observed. By a biomimetic process, the method and conditions of forming HA coating on the surface of medical silicon rubber （ abbreviated MSR ） were stndied. The results illustrate that the phosphate glass additives have obvious reinforcing effects on HA. In the percutaueous implantation test, neither clear infiltration of inflammatory cells nor marked downgrowth of epidermis was observed for the part tissue suerounded RHA. The surface modification of MSR for percutaneous access could be attained by biomimetice synthesis of HA coating.
基金
FundedbytheNationalNaturalScienceFoundationofChina(No.50472041)
