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含缬酪肽蛋白与消化系统肿瘤 被引量：1

Relationship between Valosin-containing protein and digestive tumor
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摘要 含缬酪肽蛋白(valosin-containing protein,VCP)即p97,是一种广泛存在的膜结合糖蛋白,在细胞活性中有着广泛的功能, 其总的特点是作为类似分子伴侣的作用在内质网相关的蛋白降解及细胞周期调控中起重要作用．已有许多研究证实: VCP的表达水平与食道癌、胃癌、结直肠癌、肝癌、胰腺癌等消化系统恶性肿瘤的临床病理特征之间密切相关．VCP 表达水平高者,出现复发及转移早,无瘤生存期短,预后差．本文就近年来有关VCP表达水平与消化系统肿瘤相关性的文章进行了回顾．
作者 尹义梅 穆建平 张晓岚
机构地区 河北省邯郸市第一医院消化内科 解放军 河北医科大学第二附属医院消化内科
出处 《世界华人消化杂志》 CAS 北大核心 2005年第22期2672-2676,共5页 World Chinese Journal of Digestology
关键词 急性胰腺炎 急性脑损伤 发病机制
分类号 R735 [医药卫生—肿瘤] R373.9 [医药卫生—病原生物学]
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参考文献67

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二级参考文献3

共引文献167

同被引文献16

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世界华人消化杂志
2005年 第22期

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