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肾功能不全血管钙化的机制 被引量：4

Mechanism of Vascular Calcification in Renal Dysfunction
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摘要 既往认为血管钙化是钙磷在血管壁的被动的沉积过程,近年细胞生物学和血管影像学的研究表明血管钙化是与骨生成相似的高度可调控的过程。多种机制参与了血管钙化的发生发展。其中磷,甲状旁腺素相关肽,维生素D,骨调节蛋白,脂质紊乱和炎症等在血管钙化中的发生发展中具有重要的调节作用。
作者 王希 齐永芬 唐朝枢
机构地区 北京大学第一医院心血管病研究所 北京大学医学部生理与病理生理学系
出处 《中国分子心脏病学杂志》 CAS 2005年第5期753-757,共5页 Molecular Cardiology of China
关键词 血管钙化 骨调节蛋白 肾功能不全
分类号 R692.5 [医药卫生—泌尿科学]
  • 相关文献

参考文献20

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  • 2[2]Moe SM, O'Neill KD, Duan D et al. Medial artery calcification in ESRD patients is associated with deposition of bone matrix proteins.Kidney Int, 2002, 61 : 638-647.
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二级参考文献9

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共引文献26

同被引文献66

  • 1张超,胡昭,董帅.终末期肾病维持性血液透析患者生存率和死亡的影响因素[J].中国老年学杂志,2014,34(5):1241-1243. 被引量：59
  • 2Cohn JN,Duprez DA,Grandits GA.Arterial elasticity as part of a comprehensive assessment of cardiovascular risk and drug treatment[J].Hypertension,2005,46(1):217-220.
  • 3Stephanie S,DeLoach,Raymond R,et al.Vascular stiffness:its measurement and significance for epidemiologic and outcome studies[J].Clinical Journal of the American Society of Nephrology,2008,3(1):184-192.
  • 4Adeney KL,Siscovick DS,Ix JH,et al.Association of serum phosphate with vascular and valvular calcification in moderate CKD[J].Journal of theAmericanSocietyof Nephrology,2009,20(2):381-387.
  • 5Moe SM,Chen NX.Inflammation and vascularcalcification[J].Blood Purification,2005,23(1):64-71.
  • 6Moe SM,Chen NX.Pathophysiology of calcification in chronic kidney disease[J].Circulation Research,2004,95(6):560-567.
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  • 9Kaysen GA.The microinflammatory state in uremia:cause andpotential consequences[J].Journal of theAmerican Society of Nephrology,2001,12(7):1549-1557.
  • 10Bostro K.Proinflammatory vascular calcification[J].Circulation Research,2005,96(12):1219-1220.

引证文献4

二级引证文献13

中国分子心脏病学杂志
2005年 第5期

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