HBsAg阳性者乙肝标志物及肝功检测结果分析2562例

Analysis on the hepatitis B marker and liver function of 2 562 HBsAg positive individuals

【目的】通过对正常体检者HBsAg阳性标本的不同乙肝标志物模式类型的统计,探讨HBsAg在乙肝病情及传染性方面的真正价值。【方法】检测34 532例健康体检标本中2 562例HBsAg阳性者的HBV血清学指标:表面抗原(HBsAg)、表面抗体(HBsAb)、e抗原(HBeAg)、e抗体(HBeAb)、核心抗体(HBsAb)、核心抗体IgM(HBcIgM)。以阳性项目出现的序号为该类型的代码,结合肝功能指标,分析临床意义。【结果】在每一阳性标本中,可能存在不止一种标志物,在2 562例标本中按每个阳性标本中的阳性标志物的分布可归纳成9种不同的乙肝标志物模式类型。【结论】在健康查体中的HBsAg阳性者中存在着很多特殊情况例如模式7、8、9这样的特殊类型,应做乙肝血清标志物并结合肝功能来判断其病情和传染性。

[Objective] To study the value of different hepatitis B markers on the infectivity and progress of the disease. [Methods] Six type of HB markers were determined in 2 562 HBsAg positive samples from 34 532 blood samples of norreal physical examination individuals. The liver function tests were also determined. Clinical symptoms were analyzed in accordance with these parameters. [Results] In each pasitive sample, there might be existed more than one type of marker. According to the markers existed in each sample, 9 patterns might be grouped. [Conclusion] The hepatitis B marker is varied in each HBsAg positive individual. In case of HBsAg pasitive individual, hepatitis B markers should be determined to evaluate the infectivity and progress of the disease.