摘要
目的:探讨当归注射液对鸡胚绒毛尿囊膜(chorioallantoicmembrane,CAM)血管生成的影响。方法:种蛋随机分为5组,孵育7d后,将高、中、低剂量当归注射液(Angelicasinensisinjection,ASI)及生理盐水(NS)、成纤维细胞生长因子(EGF)对照品分别加于CAM表面的载体上,作用后制备CAM标本,解剖显微镜下计数新生血管数目。结果:当归注射液具有明显的促进鸡胚绒毛尿囊膜血管生成的作用,与NS对照组相比有显著性差异(P<0.05),但药效低于EGF对照组(P<0.05)。结论:当归注射液可促进鸡胚绒毛尿囊膜血管生成。
Objective :To explore the effect of angiogenesis of angelica sinensis injection(ASI)on the chick embryo ehorioallantoie membrane (CAM)model. Methods:Fertilized eggs were incubated for 7 days at 37.8 ℃, and randomly divided into 5 groups. Then treated with NS, different dose of ASI and EGF respectively. After incubated for another 3 days, counted the number of the first and second grade blood vessels. Results: In the test experience, the proliferation of capillaries in the therapy groups were obviously increased compared with NS group (P 〈 0.05) ,but the effect was lower than EGF group (P 〈 0.05). Conelusion:ASI can stimulate angiogenesis of the chick embryo CAM model.
出处
《中医儿科杂志》
2006年第2期21-24,共4页
Journal of Pediatrics of Traditional Chinese Medicine
关键词
血管生成
绒毛尿囊膜
当归注射液
angiogenesis
chorioallantoic membrane
angelica sinensis injection