摘要
目的:解决复方三维亚油酸胶丸I在药品有效期内崩解迟缓问题。方法:在胶液中加入5%明胶量的PEG -400、抗氧化剂焦亚硫酸钠。结果:改进后工艺生产的复方三维亚油酸胶丸I的崩解时限在有限期内≤60分钟。结论:在胶液中加入5%明胶量的PEG-400、抗氧化剂焦亚硫酸钠能明显缩短复方三维亚油酸胶丸I在药品有效期内崩解时限。
Objective: Resolve the compound Trivitamin and Linolic Acid Soft Capsules I in the drugs term of validity slow problem of collapse. Methods: Join 5% PEG - 40 of the clear gum quantity in the gum liquid, burnt sulfurous acid Na of the anti- oxidizing agent. Results: After the improvement the compound Trivitamin and Linolic Acid Soft Capsules Ⅰ that craft produce of the collapse time limit are in lirnitedly extort≤60 minutes. Conclusion: Join 5% PEG-400 of the clear gum quantity in the gum liquid, the burnt sulfurous acid Na of the anti - oxidizing agent can shorten the pound Trivitamin and Linolic Acid Soft Capsules Ⅰ; obviously in the drugs term of validity collapse time limit.
出处
《黑龙江医药》
CAS
2006年第3期176-177,共2页
Heilongjiang Medicine journal
关键词
复方三维亚油酸胶丸Ⅰ
崩解时限
抗氧化剂
Compound Trivitamin and Linolic Acid Soft Capsules Ⅰ
Collapse time limit.