蛋白激酶C-δ的研究进展

Study of protein kinase C-δ

PKC-δ是PKC家族的一种亚型。目前,PKC-δ的结构及其激活与转位机制尚不明了。PKC-δ在细胞的生长、分化及凋亡、肿瘤进展中有非常重要的作用,并与肿瘤耐药性密切相关。

Protein kinase C-δ （PKC-δ） is an isoenzyme of PKC family . At present, the structure, activation and translocation mechanisms of PKC-δ are still unknow, but PKC-δ plays an important role in cell growth, differentiation and apoptosis, tumor development, and it is also associatied with tumor multidrug resistance.