肿瘤患者医院感染病原体分析

Pathogens of Nesocomial Infection in Tumor Patients

目的了解我院肿瘤患者医院感染菌株构成及耐药性,指导临床合理用药。方法对2000年1月1日～2004年12月1日,我院收治的1664例肿瘤患者的医院感染进行回顾性调查,进行病原体分析及耐药性监测。结果1664例患者发生医院感染144例,医院感染率8.91%,医院感染菌株以G-菌为主,占65.97%,其中大肠埃希菌比例最高为31.25%,其次是肺炎克雷伯菌,铜绿假单胞菌分别占13.89%、12.50%。G+菌占29.17%,其中以金黄色葡萄球菌为主占10.42%。结论根据药敏试验合理选择抗生素,以减少耐药菌株的产生。

Objective To study the kinds and drug-resistance of the pathogens of nosocomial infection in tumor patients. Methods Retrospective surveys of nosocomial infection in 1664 cases with tumors were carried out in our hospital from 2000 to 2004, the pathology analysis and the drug sensitivity test were done for cases with tumor. Results There were 144 cases of nosocomial infection from 1664 in -patients. The infection rate was 8.91%. The main pathogens were Gram-negative bacteria（65.97 % ）. Among them, Escherichia was the highest （ 31.25 % ）, then Klebsiella pneumonia （ 13. 89 % ） and pseudomonas aeruginosa（ 12.50 % ）. The number of Gram-positive organisms was 29.17%, the main pathogens were staphylococcus aurous（10. 42%）. Conclusions The antibiotics should be used reasonably, which can reduce the development of drug-resistant strains.