氮丙啶化合物的NMR与立体构型

STUDIES ON THE NMR AND CONFIGURATION OF DERIVATIVES OF AZIRIDINE

本文报导了N-(x-溴代丙烯酰)对氨基苯磺酸与四种氨基酸(乙氨酸,β-丙氨酸,L-丙氨酸和D,L-苯丙氨酸)的反应产物的结构,测定了它们的~1H,^(13)C-NMR谱。采用NMR的各种技术对谱线进行归属。根据NMR谱的差别,讨论了该类氮丙啶化合物的立体构型与N-取代基性质的关系,确定了四种氮丙啶化合物的构型。

The structures of the reaction product of p-(α-bromoacrylamido) benzene sulfonic acid and amino add (glytine,β-aminopropionic add, L-alanine and D, L-phenylalanine) are reported to be the derivatives of aziridine, 1H and 13C NMR spectra of these reaction products are recorded. In assigning the spectral lines different NMR techniques are employed. The configurations of aziridine derivatives are confirmed. Based on the differences in NMR spectra, the relationship between the configuration and the nature of N - substituent is discussed.