摘要
利用循环伏安法和交流阻抗谱,以铂电极支撑的磷脂双层膜(s-BLM)作为生物膜的模型,Fe(CN)3-6和Fe(CN)4-6为探针分子,研究了Keggin型杂多酸H3PMo12O40对磷脂双层膜电化学行为的影响,结果显示s-BLM与杂多酸H3PMo12O40之间可以发生比较强烈的相互作用,使s-BLM的通透性发生变化.这种现象的出现可能是由于在杂多酸H3PMo12O40与磷脂双层膜发生作用时引起s-BLM表面分子的排列变化,进而在膜的表面形成不可逆的微孔,而探针分子Fe(CN)3-4-6可以通过这些微孔接近电极,产生氧化还原响应.
The influence of Keg, gin type phosphomolybdic acid （ H3 PMo12 O40） on electrochemical behavior of lipid bilayer membranes as a biology membrane model was investigated by cyclic voltammetry （CV） and electrochemical impedance spectroscopy （ELS）. Experiments showed that the interaction between H3 PM012 O40 and lipid membranes leaded to Fe（ CN）6^3-/4- crossing of the s -BLM. This phenomenon was to suggested that some kinds of pores forming on the surface of membrane which decreased membrane resistibility to the probing molecules resulted from the interaction between H3PMo12O40 and lipid menbranes. This may be helpful to understand the biological activity and medical chemistry of polyoxometalates in vivo.
出处
《辽宁大学学报（自然科学版）》
CAS
2006年第2期97-100,共4页
Journal of Liaoning University：Natural Sciences Edition
基金
国家自然科学基金项目(20271024).
关键词
杂多酸
循环伏安法
交流阻抗谱
s-BLM
polyoxometalates
cyclic voltammetry
impedance spectroscopy
s - BLM.
