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颅内肿瘤放射治疗后^(18)F-氟代脱氧葡萄糖PET的临床意义

Clinical value of ^(18)F-FDG PET after radiotherapy for intracerebral tumors
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摘要 放射治疗是颅内良恶性肿瘤安全有效的治疗方法,18F—FDG PET可以提供肿瘤细胞生物特性信息,能区分颅内肿瘤放射治疗后射线损伤与肿瘤复发,灵敏度为80%-90%,特异度为 40%~100%;能预测3~4级复发恶性胶质瘤放射治疗的生存时间,预测颅内肿瘤放射治疗预后和评价治疗反应;结合其他影像方法可提高颅内肿瘤放射治疗诊断准确性。 Radiotherapy is a safe and effective management strategy for a variety of intracerebral tumors.^18F-FDG PET can provide information about the biologic characteristics of malignant cells and differentiate recurrent tumor from radiation necrosis, the sensitivity and specificity of FDG PET is 80% to 90% and 40% to 100%. ^18F-FDG PET can predict the survival in high-grade recurrent gloima. The diagnostic and prognostic information can be provided by ^18F-FDG PET. Co-registration of MR1 or CT on a single computer may improve diagnostic accuracy of PET after radiotherapy for intracerebral tumors.
作者 陈跃
出处 《国际放射医学核医学杂志》 2006年第2期97-99,共3页 International Journal of Radiation Medicine and Nuclear Medicine
关键词 ^18F-氟脱氧葡萄糖 体层摄影术 发射型计算机 脑肿瘤 放射疗法 ^18F-fluorodeoxyglucose Tomography. emission computed Brain tumors Radiotherapy
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参考文献12

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