磁源性影像结合伽玛刀治疗难治性癫痫

Magnetic source imaging combined with Gamma knife for treating refractory epilepsy

目的:探讨脑磁源性影像定位癫痫灶后结合伽玛刀放射治疗难治性癫痫的应用价值。方法:8例经磁源性影像定位癫痫灶后,指导伽玛刀放射治疗癫痫灶。结果:采用南京军区总医院的评估标准,随访疗效显示满意3例(37.5%),显著改善3例(37.5%),良好1例(12.5%),疗效差1例(12.5%)。无一例出现伽玛刀放射治疗术后功能障碍。结论:磁源性影像可以无创伤性精确定位癫痫灶,可以用于指导伽玛刀放射治疗癫痫灶。

Objective： To assess the role of magnetic source imaging combined with Gamma knife for treating refractory epilepsy. Methods： To localize the epileptic focus by magnetic source imaging and as a guidance for Gamma knife for treating refractory epilepsy in 8 patients. Results： According to the standard of effect made by Nanjing Army General Hospital, the result was satisfied in 3 cases（37.5%）, improved significantly in 3 cases（37.5%）, good result in 1 case（12.5%）, 1 of the 8 cases got bad curative effect（12.5%）. No patients experienced Gamma knife-related complications. Conclusion： Magnetic source imaging could localize the epileptic focus precisely and non-invasively. The epileptic focus could be treated by Gamma knife according to the magnetic source imaging localization.