轻症急性胰腺炎多层螺旋CT灌注成像

Multi-slice CT Perfusion Technique in the Diagnosis of Mild Acute Pancreatitis

目的:探讨多层螺旋CT灌注成像技术在轻症急性胰腺炎(MAP)中的诊断价值。方法:30例无胰腺疾病的患者和23例临床上诊断为轻症急性胰腺炎、CT分级为A^B级的患者,采用16层螺旋CT进行灌注扫描。分别测量正常胰腺组织和MAP患者胰腺组织的血流量(BF)、血容量(BV)、平均通过时间(MTT)和表面通透性(PS)的平均值,并进行分析。结果:MAP相对于正常胰腺表现为较高的灌注,以A级MAP高灌注更为明显,而B级MAP由于水肿的存在,局部产生了等灌注或低灌注效应。结论:CT灌注成像技术对于MAP的诊断具有一定的提示意义,是一种可以在临床上广泛应用的新方法。

Objective：To evaluate the role of multi-detector row CT perfusion technique in the diagnosis of mild acute pancreatitis （MAP）. Methods：Enhanced dynamic CT with perfusion technique of MAP was performed with 16-slice spiral CT in 23 patients. All of the patients were clinically diagnosed as MAP and were divided to grade A or B according to CT findings. Same CT protocol and the CT findings in 30 patients with no pancreatic disorders served as controls. Using commercial software, parameters including tissue blood flow （BF）, blood volume （BV）, mean transit time （MTT）, and vascular permeability-surface （PS） were calculated. Statistical analysis between the two groups were performed. Results：Tissues in the patients having MAP showed higher perfusion values compared with those of normal pancreas, especially in the grade A group patients showed much more higher perfusion values. Due to the existence of tissue edema, pancreatic tissues in the grade B group patients showed lower or similar perfusion values compared with those of normal pancreas. Conclusion： CT perfusion technique can be used to help identifying patients with mild acute pancreatitis, which is a promising technique in clinical application.