甲状腺相关眼病Ⅰ型患者CT与内分泌变化的相关研究

Correlation of orbital computed tomography and incretion in patients with thyroid associated ophthalmopathy-Ⅰ

目的:探讨甲状腺相关眼病Ⅰ型患者CT表现与其内分泌变化之间的相关性。方法:对38名甲状腺相关眼病Ⅰ型患者(患者组)及50名健康成人(对照组)行眼眶冠轴位CT扫描,测量各眼外肌大小及CT值,并将结果与其内分泌变化作相关性分析。结果:患者组与对照组眼外肌的大小及CT值差异均有显著性意义,而且患者组眼外肌最大径线值与T3、T4测定值之间呈正相关,与促甲状腺激素(TSH)测定值之间呈负相关。结论:甲状腺相关眼病Ⅰ型患者CT表现特点与其内分泌变化关系密切,可作为临床随访的有效指标之一。

Objective： To evaluate the correlation of orbital computed tomography and incretion in patients with thyroid associated ophthalmopathy- Ⅰ. Methods： Seventy-six orbits of 38 patients with thyroid associated ophthalmopathy were evaluated by CT in respect to the density and the size of extraocular muscles, and 100 normal orbits of 50 healthy person were evaluated with the same indices for comparison. Results ： There was significant difference in the density and the size of extraocular muscles between the patients and the healthy adults. The maximal size of extraocular muscles were positive correlation with T3, T, in TAO- Ⅰ , and negative correlation with TSH. Conclusion： The manifestation of orbital CT may be a good index in the following survey of thyroid associated ophthalmopathy- Ⅰ.