摘要
应用超薄切片技术对水泡性口炎病毒(VSV)在BHK-21细胞上的形态发生和早期发育进行了观察。结果表明,VSV能导致BHK-21细胞圆缩,胞浆严重空泡化,线粒体嵴断裂及空泡化;病毒在细胞浆内复制、增殖,在细胞膜上以出芽方式获得囊膜而成熟。
The morphopoiesis and progenesis of the vesicular stomatitis virus in baby hamster kidney celI-21（BHK-21） were observed by using electron microscope. The results showed that BHK-21 cell became round in shape; a lot of vacuoles occurred in its cytoplasm; the mitochondria vacuolated and the ridge of mitochondria ruptured. Virus replicated and then multiplied within the cytoplasm. It was matured through obtaining the capsid from cellular membrane via budding.
出处
《中国兽医学报》
CAS
CSCD
北大核心
2006年第3期265-267,共3页
Chinese Journal of Veterinary Science
基金
国家自然科学基金资助项目(30270994)
关键词
水泡性口炎病毒
BHK-21细胞
细胞病变
超微结构
vesicular stomatitis virus
BHK-21 cells
cytopathogenic effect （CPE）
ultrastructural features
