慢性活动性EB病毒感染的诊断标准和治疗

Diagnostic Criteria and Treatment of Chronic Active Epstein - Barr Virus Infection

慢性活动EB病毒(CAEBV)感染是一种少见的发生在有免疫能力个体的严重综合征,主要表现为EBV感染后出现慢性或复发性传单样症状伴随EBV抗体的异体改变,病程中可出现严重的或致死的并发症。目前国内尚无CAEBV的诊断标准。参照国外最新研究进展,本文就其发病机制、诊治方案做一介绍,以提高临床对CAEBV的诊治水平。

Chronic active Epstein - Barr virus infection （CAEBV） is an uncommon outcome of EBV infection and may present as severe of fulminant syndrome with high - mortality. It is characterized by chronic or recurrent infectious mononucleosis - like symptoms persisting over a long time and by an unusual pattern of anti - EBV antibodies. Although it occurs in immunocompetent individuals, a number of subtle immunologic defects have been reported in patients with CAEBV. Up to now, there are still no diagnoatic criteria of CAEBV in China, so the author introduce it with respect to its diagnosis, history, pathogenesis and therapeutic approaches.