2Joost H,Thorens B.The extended GLUT-family of sugar \polylol transport facilitators:Nomenclature,sequence,characteristic and potential function of its novel members.Molecular Membrane Biol,2001,18:247
3Erik L,Panthea T,Kelly C,et al.HER2 signaling increases the rate of HIF-1a synthesis:Novel mechanism for HIF-1-Mediated Vasular endothelial growth factor expression.Molecular and Cellular Biology 2001,21:3995
4Zhong H,Chiles K,Feldser D,et al.Modulation of hypoxia-inducible factor-1a expression by the epidermal growth factor\phosphatidylinositol 3-Kinase\PTEM\AKT\FRAP pathway in human prostate cancer cells implications for tumor angiogenesis and the rapeutics.Cancer Res,2000,60(6):1541
5Kasuno K,Takabuchi S,Fukuda K,et al.Semenza GL,Hirota K 2004Nitric oxide induces HIF-1a that is dependent on MAPK and phosphatidylinositol 3-Kinase sigaling.J Biol chem,279:2550
6Richard DE,Merra E,Gothie,et al.P42\44 Mitogen-activated protein kinases phosphorylate HIF-1a and Enhance the Transcriptioual Activity of HIF-1.J Biol Chem,1999,274(46):32631
8Haber R S,Rathan A,Weiser KR,et al.GLUT1 glucose transporter expression in colorectal carcinoma:a marker for poor prognosis.Cancer,1998,83(1):34
9Vannucci SJ.Reinhart R,Maher F,et al.Alterations in GLUT1,and GLUT3 glucose transporter gene expression following unilateral hypoxia ischemia in the immature rat brain.Brain Res,1998,107
10Zhong H,De Marzo AM,Laughner E,et al.Overexpresssion of hypoxia inducible factor-1a in common human cancers and their metastasis,Cancer Res,1999,59(22):5830
二级参考文献61
1Semenza G. Signal transduction to hypoxia inducible factor 1 [J].Biochem Pharmacol, 2002, 64(5 6):993- 998.
2Chun YS, Kim MS, Park JW. Oxygen dependent and independent regulation of HIF 1alpha [J]. J Korean Med Sci, 2002, 17(5):581- 588.
3Maxwell PH, Wiesener MS, Chang GW, et al. The tumour suppressor protein VHL targets hypoxia inducible factors for oxygen dependent proteo lysis [J]. Nature, 1999, 399(6733): 271- 275.
4Epstein AC, Gleadle JM, McNeill LA, et al.C.elegans EGL 9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation [J]. Cell, 2001, 107(1):43- 54.
5Lando D, Peet DJ, Whelan DA, et al. Asparagine hydroxylation of the HIF transactivation domain: a hypoxic switch [J]. Science,2002, 295(5556):858- 861.
6Chun YS, Choi E, Kim G, et al. Zinc induces the accumulation of hypoxia inducible factor (HIF) 1alpha, but inhibits the nuclear translocation of HIF 1beta, causing HIF 1 inactivation [J]. Biochem Biophys Res Commun, 2000, 268 (2):652- 656.
8Brune B, Zhou J. The Role of Nitric Oxide (NO) in Stability Regulation of Hypoxia Inducible Factor 1alpha (HIF 1alpha) [J]. Curr Med Chem, 2003, 10 (10):845- 855.
9Liu Y, Christou H, Morita T, et al.Carbon monoxide and nitric oxide suppress the hypoxic induction of vascular endothelial growth factor gene via the 5 enhancer [J]. J Biol Chem, 1998, 273(24):15257- 15262.
10Huang LE, Willmore WG, Gu J, et al. Inhibition of hypoxia inducible factor 1 activation by carbon monoxide and nitric oxide: Implications for oxygen sensing and signaling [J]. J Biol Chem, 1999, 274(13):9038- 9044.