健康教育对慢性乙型肝炎合并抑郁症患者的影响

Effect of health education on patients with chronic hepatitis B accompanied with depression

目的调查慢性乙型肝炎患者抑郁症状发生率并探讨健康教育对抑郁症状及肝功能的影响。方法采用Zung抑郁自评量表(SDS)对106例慢性乙型肝炎患者进行测评。将抑郁指数≥0.5的56例患者随机分为干预组28例,对照组28例。干预组在住院期间药物治疗的同时并进行健康教育与心理社会干预,分别于入出院时SDS、肝功能、HBV DNA检测,对病情恢复时间进行评估。结果慢性乙型肝炎并抑郁情绪检出率为52.83%,SDS总分均值54.98±10.50,与国内常模比较,高度显著性差异(P<0.01),经健康教育与心理社会干预后,干预组抑郁指数显著降低(P<0.01),病情恢复时间(肝功能、HBV DNA复常时间)显著缩短(P<0.05)。结论慢性乙型肝炎患者常合并忧郁症状,健康教育与心理社会干预可改善抑郁症状及机体的免疫功能,提高抗病毒能力。

Objective To find out the incidence rate of depression in patients with chronic hepatitis B and investigate the effect of health education to depression, the function of liver and HBV DNA. Methods 106 patients with chronic hepatitis B were assessed with SDS. Patients with depressive index over 0.5 were randomly divided into the intervention group （28） and the control group （28）. After health education, all 56 patients were assessed with SDS. The function of liver, HBV DNA and recovery time were examined again. Results The incidence rate of depression in patients with chronic hepatitis 13 was 52.83%. Health education reduced the severity of depression and improved the function of liver, HBV DNA, while control group made no significant progress. Conclusion Depression is common among patients with chronic hepatitis B and psychosocial intervention can help patient cope with depression and benefit them psychologically and physically.