红皮病性银屑病的诊断与治疗(附60例分析)

The Analyses of 60 samples on Erythroderma Psoriaticum

目的分析红皮病型银屑病致病因素及治疗方法。方法回顾性总结60例红皮病性银屑病患者在复方甘草酸苷(SNMC)、支持疗法、抗生素治疗基础上,分为两组并分别给予阿维A和甲氨喋呤(MTX),分3个阶段进行治疗。结果男性居多,>50岁发病率高占78.3%,不恰当的用药和上呼吸道感染是主要发病因素。阿维A组有效率90%,甲氨喋呤组有效率为93.3%,平均痊愈时间用49.25 d4、5.62 d,副作用阿维A组略高于甲氨喋呤组,两组间差异无显著性(χ2=1.62,P>0.05)。结论复方甘草酸苷、支持疗法、抗生素、免疫抑制剂或维甲酸制剂,是治疗红皮病性银屑病安全有效的方法。

Objective Objective to analyze the predisposition and treatment effects of erythroderma psoriaficum. Methods Retrospective summary 60 samples of erythroderma psoriaticum can be divided into two groups on the basis of SNMC, supportive therapy and antibiotic treatment. These two groups should be given acitretin and MIX respectively during three stages. Results The incidence was as high as 86.7% among the male who are over 40. The main causes were unreasonable usage of medicine and upper respiratory tract infection. The cure rate of acitretin was 90% ,and the cure rate of MIX was 93.3%. The average cure time was 49.25 days and 45.26 days. The negative effects of acitretin were more than those of MIX. There was no distinctive difference between the two groups（ X^2 = 1. 62, P 〉 0.05）. Conclusion It is suggested that the method of using SNMC, supportive therapy, antibiotic treatment and immuno- suppressive drugs or retinoic acid should be safe and effective.