米力农的合成

Synthesis of Milrinone

米力农的合成⒇徐芳任进知陈建东廖清江（中国药科大学计划生育药物研究中心，南京２１０００９）关键词米力农；正性肌力作用；充血性心力衰竭；合成米力农（ｍｉｌｒｉｎｏｎｅ），化学名称为１，２－二氢－６－甲基－２－氧－５－（４－吡啶基）－菸酮腈，它是一类既非...

This paper describes a synthetic method of a new congestive heart failure agent milrinone(Ⅲ)(1,2 dihydro 6 methyl 2 oxo 5 (4 pyridinyl) nicotinnitrile) which was prepared from γ picoline through a three step process, and some reaction conditions were modified.