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以父母为供体的半相合干细胞移植治疗儿童白血病的初步研究 被引量:1

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摘要 目的探讨干细胞移植治疗儿童白血病的新方法。方法4例复发的儿童白血病患者,以父母为供者,以氟达拉宾、白消安、环磷酰胺组成预处理方案,采用外周血干细胞和骨髓联合移植的方法进行治疗。结果4例均获得造血重建,未出现严重的移植相关毒性。2例发生急性移植物抗宿主病,1例发生严重慢性移植物抗宿主病,治疗后均恢复。结论以父母为供者进行半相合移植治疗儿童白血病是可行的。
出处 《中国综合临床》 北大核心 2006年第6期551-552,共2页 Clinical Medicine of China
基金 厦门市科技攻关项目(3502Z20024017)
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  • 1Morton J, Hutchins C, Durrant S. Granulocyte-colony-stimulating factor (G-CSF)- primed allogeneic bone marrow: significantly less graft-versus-host disease and comparable engraftment to G-CSF-mobilized peripheral blood stem cells. Blood, 2001; 98:3186 -3191.
  • 2Frassoni F, Labopin M, Bacigalupo A, et al. Expanded mesenchymal stem cell ( MSC), co-infused with HLA identical hemopoitetic stem cell transplantats, reduced acute and chronic graft versus hostdisease: a matched pair analysis bone marrow transplant, 2002; 29(Suppl 2): S21.
  • 3Nash RA,Pineiro LA,Storb R,et al.FK506 in combination with methotrexate for the prevention of graft-versus-host-disease after marrow transplantation from matched unrelated donors[].Blood.1996
  • 4Anasetti C,Hansen J.Effect of HLA incompatibility in marrow transplantation from unrelated and HLA-mismatched related donors[].Transfusion Science.1994
  • 5Allison AC,Engui EM.Purine metabolism and immunosuppressive effects of mycophenolate mofetil (MMF)[].Clinical Transplantation.1996
  • 6Sollingor HW.Mycophenolate mofetil for the prevention of acute rejection in primary cadaveric renal allograft recipients[].Transplantation.1998
  • 7Nademance A,Schmidt GM,Parker P,et al.The outcome of matched unrelated donor bone marrow transplantation in patients with hematologic malignancies using molecular typing for donor selection and graft-versushost disease prophylaxis regimen of cyclosporine, methotrexate and prednisone[].Blood.1995
  • 8Basara N,Blau WI,Romer E,et al.Mycophenolate mofetil for the treatment of acute and chronic GVHD in bone marrow transplant patients[].Bone Marrow Transplantation.1998
  • 9Bornhauser M,Schuler U,Porksen G,et al.Mycophenolate mofetil and cyclosporine as graft-versus-host disease prophylaxis at allogeneic blood stem cell transplantation[].Transplantation.1999
  • 10Fulton B,Markham A.Mycophenolate mofetil: a review of its pharmacodynamic and pharmacokinetic properties and clinical efficacy in renal transplantation[].Drugs.1996

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  • 1孟庆丰,吴敏,张云霞,岳同云,宋晓时,刘杰,王桂英,孟彤.神经母细胞瘤65例临床分析[J].实用肿瘤学杂志,1995,9(2):61-62. 被引量:2
  • 2鹿全意,郭勇,张鹏,牛小青,蔡玉贤,陈小燕.HLA位点不全相合的异基因干细胞移植治疗白血病的临床分析[J].临床血液学杂志,2005,18(6):323-325. 被引量:1
  • 3唐锁勤,黄东生,王建文,冯晨,杨光.大剂量化疗造血干细胞移植治疗IV期神经母细胞瘤的长期疗效研究[J].中国当代儿科杂志,2006,8(2):93-96. 被引量:27
  • 4Matthay KK, Villablanca JG, Seeger RC, Stram DO, Harris RE, Ramsay NK, et al. Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cisretinoicacid. Children's Cancer Group [J]. N Engl J Med, 1999,341(16) : 1165-1173.
  • 5George RE, Li S, Medeiros-Nancarrow C, Neuberg D, Marcus K, Shamberger RC, et al. High-risk neuroblastoma treated with tandem autologous peripheral-blood stem cell-supported transplantation: long-term survival update [ J ]. J Clin Oncol, 2006, 24 ( 18 ) :2891-2896.
  • 6Childs R, Chernoff A, Contentin N, Bahceci E, Schrump D, Leitman S, et al. Regression of metastatic renal-cell carcinoma after nonmyeloablative allogeneic peripheral-blood stem-cell transplantation[J]. N Engl J Med, 2000, 343(11):750-758.
  • 7Inoue M, Nakano T, Yoneda A, Nishikawa M, Nakayama M, Yumura-Yagi K, et al. Graft-versus-tumor effect in a patient with advanced neuroblastoma who received HLA haplo-identical bone marrow transplantation [ J ]. Bone Marrow Transplant, 2003,32 ( 1 ) : 103-106.
  • 8Matthay KK, Seeger RC, Reynolds CP, Stram DO, O'Leary MC, Harris RE, et al. Allogeneic versus autologous purged bone marrow transplantation for neuroblastoma: a report from the Children's Cancer Group[J]. J Clin Oncol, 1994, 12( 11 ) : 2382-2389.
  • 9Pedrazzoli P, Da Prada GA, Giorgiani G, Schiavo R, Zambelli A, Giraldi E, et al. Allogeneic blood stem cell transplantation after a reduced-intensity, praparative regimen: a pilot study in patients with refractory malignancies [ J ]. Cancer, 2002,94 ( 9 ) : 2409- 2415.
  • 10Kim EK, Kang HJ, Park JA, Choi HS, Shin HY, Ahn HS. Retrospective analysis of peripheral blood stem cell transplantation for the treatment of high-risk neuroblastoma[ J]. J Korean Med Sci, 2007,22 (Suppl) : S66-72.

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