3,5-二氧代环己烷羧酸乙酯的合成方法改进

Synthesis method improvement of 3,5-Diketo-1-carbethoxycyclohexane

以3,5-二羟基苯甲酸为原料,经Pd／C[w(Pd)=5%]催化转移加氢合成3．5-二氧代环己烷羧酸, 然后酯化生成3-乙氧基-5-乙氧羰基-2-环己烯酮,最后水解得到3,5-二氧代环己烷羧酸乙酯。各产物通过1HNMR 和GC-MS得以确认。

3,5-Dioxocyclohexanecarboxylic acid was prepared from 3,5-dihydroxybenzoicacid through transfer hydrogenation with 5% Pd/C as catalyst. 3,5-diketo-1-carbethoxycyclohexane has been prepared through hydrolysis of 3-ethoxy-5-carboethoxy-2-cyclohexenon-e which was synthesized from 3,5-dioxocyelohexanecarboxylic. The structures were confirmed by ^1HNMR and GC-MS.