Remission of primary low-grade gastric lymphomas of the mucosa-associated lymphoid tissue type in immunocompromised pediatric patients

我们报导联系 mucosa 的淋巴组织(麦芽) 的主要胃的淋巴瘤的宽恕在二免疫打损害小儿科的病人。病人 1，在免疫的一个 14 岁的男孩损害了未知原因的状态，抱怨了重复腹的疼痛。考试与本地侵略和淋巴节点参与揭示了胃的麦芽。浆液 anti-Helicobacter pylori (H pylori ) 抗体是积极的。H pylori 根除被沉溺于它的不利效果。麦芽损害自发地在没有为淋巴瘤的任何治疗的下一 24 个月的 regressed。病人 2，一个 6 岁的男孩，为 adrenoleukodystrophy 的治疗经历了脐带血移植。他是为在移植以后的 graft-versus-host 疾病的管理抑制免疫力的药。恶心和便血出现了，进一步的考试与 H pylori 胃炎揭示了胃的麦芽。独自为 H pylori 感染由药组成的治疗根除了 H pylori 并且完全也解决了病人的麦芽损害。病人们 1 和 2 被跟随在上面在 10 年和 3 年的经期上，分别地没有恶化的任何症状。在结论， MALT 类型的胃的淋巴瘤能被保守疗法甚至在免疫治好损害小儿科的病人。

We report the remission of primary gastric lymphoma of the mucosa-associated lymphoid tissue （MALT） type in two immunocompromised pediatric patients. Patient 1, a 14-year-old boy in an immunocompromised state of unknown cause, complained of repeated abdominal pain. Examinations revealed gastric MALT with local invasion and lymph node involvement. Serum anti-Helicobacter pylori （H pylon） antibody was positive. H pylori eradication was abandoned due to its adverse effects. The MALT lesion spontaneously regressed over the next 24 months without any treatment for lymphoma. Patient 2, a 6-year-old boy, underwent cord blood transplantation for the treatment of adrenoleukodystrophy. He was administered immunosuppressants for graft-versus-host disease after transplantation. Nausea and hematochezia appeared and further examinations revealed gastric MALT with H pylori gastritis. Treatment consisting of medication for the Hpylori infection alone eradicated the Hpylori and completely resolved the patient＇s MALT lesion, as well. Patients i and 2 were followed up over periods of 10 years and 3 years, respectively, without any signs of relapse. In conclusion, gastric lymphoma of the MALT type can be cured by conservative treatment even in immunocompromised pediatric patients.