五倍子对鲤鱼细菌性败血症的药效试验初报

Pharmacodynamic Studies on Chinese nutgall against Bacterial Septicemia of Carp (Cyprinus carpio)

以0.5%和1.0%五倍子药饵饲喂鲤鱼,通过肝脏和血液指标的测定,研究五倍子对鲤鱼细菌性败血症的药效。结果表明:攻毒前饲喂药饵16d,防治组肝脏酸性磷酸酶和碱性磷酸酶活性升高(P<0.05);攻毒并给药14d,防治组和治疗组血清肌酐、尿酸、尿素氮含量,谷丙转氨酶、碱性磷酸酶活性均由8d时高于空白组(P<0.05)降低到正常值或与之基本接近(P>0.05);防治组和治疗组死亡率较对照组极显著降低(P<0.01),并且防治组明显低于治疗组(P<0.05),0.5%和1.0%药饵组间无显著差异(P>0.05)。因此,五倍子增强了鱼体非特异性免疫能力,对细菌性败血症有良好的预防和治疗作用。

Carp were fed with medicated diet added with Chinese nutgall at the weight rate of 0.5% or 1.0% , by examining the indices of liver and blood , the effect of Chinese nutgall to carp bacterial septicemia was studied . The results showed that at the 16 days of medicated diet before infection , the hepatic ACP and AKP activity of prevention and cure group were significantly higher than blank group （P〈 0.05）;at the 14 days of medicated diet after infection , the blood CRE, UA, UN, ALT and AKP of cure group and prevention and cure group decreased to the normal levels or approach to them （P〉0.05） from the significantly pathologic higher levels of 8 days （P〈0.05） ; the mortalities of prevention and cure groups and cure groups had very significant decrease compared to control group （P〈0.01）, prevention and cure groups were very significantly lower than cure groups （P〈0.05）, and there was no significant difference between medicated diet of 0.5% and 1.0% （P〉 0.05）. Furthermore, Chinese nutgall can improve the nonspecific immunity ability of carp , and have a significant effect of preventing and curing the fish bacterial septicemia.