非瓣膜病心房纤颤与抗血栓栓塞相关性研究

The Study on Correlation between Nonvalvular Atrial Fibrillation and Antiembolism in Patients

通过观察136例非瓣膜病心房纤颤(NVAF)以及76例非房颤性心脏病患者并随访825±365天.研究非瓣膜病心房纤颤与抗血栓栓塞的相关性。结果:NVAF中,慢性房颤组123例中.26例脑栓塞(21.2％),其中14例死亡(11.3％),阵发性房颤组13例中2例脑栓塞(15.3％)死亡1例(7.6％),非房颤心脏病组76例中3例脑栓塞(3.9％),1例死亡(1.7％)。NVAF与非房颤心脏病脑栓塞之比是20.5％:3.9％(P<0.001)。死亡率之比是11.0％:1.3％(P<0.01)。因此NVAF与血栓栓塞事件紧密相关,积极采取抗凝是治疗NVAF一个重要的措施。

To investigate the relationship between nonvalvular atrial fibrillation (NVAF) and embolism, we observed 136 patients who underwent NVAF and 76 nonfibrillation were followed up for 825 + 365 days. Results:16 patients died, 14 patients (11. 3% ) with chronic Atrial Fibrillation (AF)and 1 patient (7. 6% ) with Paroxysmal Atrial Fibrillation (PAF),1 patient (1.7%) with nonfibrillation heart disease. 31 patients had cerebral embolism: 26 patients (15. 3% ) had PAF. 3 patients (3.9%)had nonfibrillation heart disease. Actually, embolism was more often in atrial fibrillation than in nonfibrillation patients(20. 5% versus 3.9%, P<0. 001) and mortality higher in atrial fibrillation than in nonfibrillation patients. (11. 0% versus 1. 3%, P<0. 01). These results suggest that NVAF was positively correlated with cerebral embolism. So we thinkthe use of anticoagulation is an important measure in the treatment of patients with NVAF.