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纳洛酮催醒对胸部疾患全麻术后镇痛药芬太尼用量的影响

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摘要 目的:观察纳洛酮全麻术后催醒对镇痛药芬太尼用量的影响.方法:选择ASA分级1~2级,在全麻下行胸部手术的患者60例,分为自动苏醒组(A组)和纳洛酮催醒组(B组).术后应用芬太尼行静脉自控镇痛(PCIA).记录患者术后首次要求镇痛的时间,术后1、2、6、24、48h的疼痛评分,镇静评分,芬太尼用量及术后恶心、呕吐的情况.结果:从手术结束到患者首次要求镇痛的时间:A组40.38±12.65min,B组10.51±8.36min(P<0.01).B组术后48h内的芬太尼用量1.32±0.25mg,显著高于A组0.85±0.22mg(P<0.01).术后恶心、呕吐的发生率分别为16.7%和33.3%(P<0.05).结论:全麻术后若需行PCIA者,应避免使用纳洛酮催醒,以免术后加大芬太尼的用量而产生较多的副作用.
出处 《南通大学学报(医学版)》 2006年第3期204-204,206,共2页 Journal of Nantong University(Medical sciences)
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