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蛋白质组学技术筛选子宫内膜异位症标志物的应用进展 被引量:2

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摘要 子宫内膜异位症发病率和复发率均很高,因此,需对子宫内膜异位症的发病机制有更深入的了解。寻找子宫内膜异位症标志物,不仅可以反映细胞的病理改变、疾病发生发展过程中的分子变化,从而了解子宫内膜异位症的发病机制,而且可为异位症诊断和导向治疗打下基础。现在,以蛋白质双向凝胶电泳、质谱为代表的蛋白质组学技术已成为发现新的分子标记物的有力工具,在肿瘤研究中应用甚广。现就蛋白质组学技术用于寻找子宫内膜异位症标志物的研究作一综述。
出处 《现代妇产科进展》 CSCD 北大核心 2006年第4期302-304,共3页 Progress in Obstetrics and Gynecology
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  • 1Cui JF,Liu YK,Pan BS,et al.Differential proteomic analysis of human hepatocellular carcinoma cell line metastasis-associated proteins[J].J Cancer Res Clin Oncol,2004,130:615-622
  • 2Wang H,Kachman MT,Schwartz DR,et al.Comprehensive proteome analysis of ovarian cancers using liquid phase separation,mass mapping and tandem mass spectrometry:a strategy for identification of candidate cancer biomarkers[J].Proteomics,2004,4:2476-2495
  • 3Zhang Z,Bast RC Jr,Yu Y,et al.The three biomarkers identified from serum proteomic analysis for the detection of early stage ovarian cancer[J].Cancer Res,2004,64:5882-5890
  • 4Rao S,Aberg F,Nieves E,et al.Identification by mass spectrometry of a new α-tubulin isotype expressed in human breast and lung carcinoma cell lines[J].Biochemistry,2001,40:2096-2103
  • 5Guo J,Yang EC,DeSouzal L,et al.A strategy for high-resolution protein identification in surface-enhanced laser desorption/ionization mass spectrometry:Calgranulin A and chaperonin 10 as protein markers for endometrial carcinoma[J].Proteomics,2005,5:1953-1966
  • 6Joshi SG,Zamah NM,Raikar RS,et al.Serum and peritoneal fluid proteins in women with and without endometriosis[J].Fertil Steril,1986,46:1077-1082
  • 7Mathur S,Chihal H J,Homm R J,et al.Endometrial antigens involved in the autoimmunity of endometriosis[J].Fertil Steril,1988,50:860-863
  • 8Mathur S,Garza DE,Smith LF.Endometrial autoantigens eliciting immunoglobulin (Ig) G,IgA,and IgM responses in endometriosis[J].Fertil Steril,1990,54:56-63
  • 9Sharpe KL,Bertero MC,Vernon MW.Detection of a progesterone-induced secretory protein synthesized by the uteri but not the endometriotic implants of rats with induced endometriosis[J].Fertil Steril,1991,55:403-410
  • 10Sharpe KL,Vernon MW.Polypeptides synthesized and released by rat ectopic uterine implants differ from those of the uterus in culture[J].Biol Reprod,1993,48:1334-1340

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  • 1郎景和.子宫内膜异位症研究的新里程[J].中华妇产科杂志,2005,40(1):3-4. 被引量:278
  • 2蔡净亭,张怡,李梦熊,刘惠宁,张瑜,彭国庆.乙酰肝素酶mRNA在子宫内膜异位症和子宫腺肌病中表达的研究[J].现代妇产科进展,2006,15(2):100-102. 被引量:1
  • 3蒋红清,李亚里.子宫内膜异位症药物及生物治疗新进展[J].现代妇产科进展,2006,15(2):134-136. 被引量:25
  • 4郎景和,冷金花,周应芳,郁琦,肖红梅,曹斌融,张震宇,梁志清,刘彦,谢梅青,王立杰.子宫内膜异位症[J].现代妇产科进展,2006,15(3):161-172. 被引量:106
  • 5Sharpe-Timms KL. Endometrial anomalies in women with endometrio-sis[ J]. Ann NYAcad Sci,2001,943 : 131.
  • 6Fowler PA, Tattum J, Bhattacharya S, et al. An investigation of the efffects for endomistriosis on the proteome of human eutopic endometrium : a heterogeneous tissue with a complex disease [ J~. Proteomics ,2007,7 (1) :130.
  • 7Kyama CM, T Jampens D, Mihalyi A,et al. ProteinChip technology is a useful method in the pathogenesis and diagnosis of endometriosis: a preliminary study [ J ]. Fertil Steril. 2006,86 ( 1 ) :203.
  • 8Tabibzedeh S,Becker JL,Parsons AK,et al. Endometriosis isassociated with alterations in the relative abundance of proteins andIL-10 in the peritoneal fluid [ J ]. Front Biosci ,2003,8:70.
  • 9Yeaman GR, Collins JE, Lang GA. Autoantibody responses to carbohydrate epitopes in endometriosis[J]. Ann NY Acad Sci ,2002,955 : 174.
  • 10Zhang H, Niu Y ,Feng J, et al. Use of proteomic analysis ofendometriosis to identify different protein expression in patientswith endometriosis versus normal control[ J ]. Fertil Steri1,2006,86(2) :274.

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