摘要
应用流式细胞术和细胞免疫荧光染色技术，对４２例膀胱癌ｒａｓＰ２１和Ｐ５３癌基因蛋白行流式分析。结果显示，Ｐ２１和Ｐ５３表达与肿瘤ＤＮＡ倍体和肿瘤病理分级及预后密切相关，提示测定Ｐ２１和Ｐ５３在膀胱癌的表达，对预后能作出客观判断。
ras P21 and P53 expression were examined in 42 transitional cell carcinoma of the bladder with flow cytometry and cyto-immunoflurescence statining techique.The results showed expression of P2l and P53 were apparently relation to pathological grading,DNA ploid and prognosis The results suggest that P21 and P53 protein assay is an objective indicator of prognosis.
出处
《天津医科大学学报》
1996年第2期48-50,共3页
Journal of Tianjin Medical University
关键词
膀胱肿瘤
癌
移行细胞癌
癌基因蛋白
Bladder
Transitional cell carcinoma
Oncogene protein prognosis
Flow cytometry
