男性新生儿血红蛋白正常参考值与中国地理因素

Normal reference values of hemoglobin of male newborn infants and geographical factors in China

目的:为制定中国男性新生儿血红蛋白正常参考值的统一标准提供科学依据。方法:收集了中国78个单位用氰化高铁血红蛋白(HiCN)法测定的5169例男性新生儿血红蛋白正常参考值,运用相关分析和回归分析的方法,研究了其与地理因素的关系。结果:发现男性新生儿血红蛋白正常参考值与中国地理因素之间有很显著的相关关系(F=17.93)。用逐步回归分析的方法推导出了一个回归方程:Y=156.8+0.01670X1+0.4140X3-0.008596X5±25.1。结论:如果知道了中国某地的地理因素,就可以用回归方程估算这个地区的血红蛋白正常参考值。依据血红蛋白正常参考值与地理因素的依赖关系把中国分为青藏区、西南区、西北区、东南区、华北区、东北区等六个区。

Objective： In order to provide scientific basis for formulating the normal reference value standards of hemoglobin of Chinese male newborn infants（MNI）. Methods： The normal reference values ef hemoglobin of 5169 MNI in 78 areas in China,which were determined by HiCN method,were collected and studied to be relative to geographical factors using relative and regressive analysis methods. Results： There was significant correlation between the normal reference values of hemoglobin of MNI and the geographical factors in China（F = 17.93）, using the method of mathematical regression analysis to produce a regression equation： Y = 156.8 ＋ 0. 01670x1 ＋ 0.4140x3 - 0. 008596xs ＋ 2.5. 1. Conclusion： If the geographical factor in some area in China is known, the normal reference values of hemoglobin of MNI in this area can be reckoned by using regression equation. According to this correlation, China can be divided into six regions： Qingzang, Southwest, Northwest, Southeast, North China and Northeast regions.