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呼肠病毒基因组片段S1编码蛋白的研究进展 被引量:1

Research Progress of Proteins Encoded by Reovirus S1 Genome Segment
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摘要 呼肠病毒共有3个血清型,不同型之间S1片段编码蛋白的同源性小于26%,其它9个片段编码蛋白的同源性都在86%以上。S1片段是双顺反子,编码σ1和σ1s,这两个蛋白决定了呼肠病毒的感染性、致病性和毒力。本文综述了σ1、σ1s的结构与功能的研究进展。 Reovirus includes 3 serotypes. Homology of proteins encoded by S1 genome segment was less than 26% between serotypes, while that of viral proteins encoded by other 9 segments was all more than 86%. Reovirus infectivity and pathogenicity were determined by σ1 and σ1s encoded by segment S1. Structure and function of the two proteins were also reviewed in this paper.
作者 宋立华 端青
出处 《现代生物医学进展》 CAS 2006年第3期33-35,共3页 Progress in Modern Biomedicine
基金 国家自然科学基金资助项目(No.30471555) 军事医学科学院创新启动基金项目(No.200408183)
关键词 呼肠病毒 sigmal蛋白 slgmals蛋白 Reovirus Sigmal protein Signals protein
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